https://apnews.com/article/hawaiian-airlines-flight-turbulence-updates-860aa76287bad2cef7cfb308f18fa9dc

This is why I take my final bathroom break at about the final hour mark of the flight. That normally aligns just after the breakfast or final snack service.

Ideally, you want to be seated and secured before the plane begins descending into possible weather disturbances.